What is ERA in IVF? Understanding the Endometrial Receptivity Array at Nex IVF Centre

For In Vitro Fertilization (IVF), success relies on many factors including having the environment of the uterus suitable for the implantation of the embryo. The Endometrial Receptivity Array (ERA), is one of the most important discoveries in IVF technology. The ERA test in IVF helps determine the optimal time for embryo transfer by assessing the endometrial receptivity, increasing the chances of a successful pregnancy. However, this test is critical in determining the best window for embryo transfer to give the best indication of a successful pregnancy.

What is ERA?

The Endometrial Receptivity Array (ERA) is a diagnostic test that measures the expression of the genes in the lining of the uterus (endometrium). It helps decide the best time for embryo transfer during IVF by looking at how receptive the uterus is to an embryo implant.

Under the influence of hormone signals, the endometrium changes during the processes of embryo implantation. It can fail implantation if the timing is off, which is a big reason why IVF cycles fail. By determining the exact window, ERA provides the exact window when the endometrium is most receptive to implantation.

How Does ERA Work?

The endometrial biopsy or the common ERA test is a very simple biopsy of the endometrial lining. The sample is collected during a natural cycle, or a simulated cycle where your uterus has been prepared to receive an embryo. After the biopsy, the lab is analyzed for gene expression corresponding with the ideal implantation window. The results can be based on the doctors to adjust the IVF cycle for personal timing.

Why is ERA Important in IVF?

For many struggling couples trying to conceive, embryo transfer timing is a big player in whether or not IVF works. Typically, traditional IVF methods require a general approach to timing, but each woman’s body is different. The personalized solution that ERA offers to each individual’s endometrial receptivity tailors the transfer to fit each individual. This is helpful, especially for women who have gone through repeated IVF failure, with good quality embryos.

Benefits of ERA Testing

• Increased Success Rates: ERA can also pinpoint the exact time to transfer the embryo to which it predicts maximum implantation rates, increasing the success rate in IVF.
• Personalized Treatment: ERA produces more accurate data which IVF doctors can then use to develop a more personalized approach.
• Prevents Wasted Cycles: Being able to exclude or identify poor prognosis embryos will prevent unnecessary embryo transfers and save time and resources by greatly increasing the chance of a successful transfer on the first attempt.
• Improves Pregnancy Outcomes: The chances for a successful pregnancy through IVF are increased dramatically if you time the threesome precisely.

When should you consider ERA testing?

• Repeated IVF Failures: ERA can help if you’ve had multiple unsuccessful IVF cycles even though you have good-quality embryos.
• Repeated Miscarriages: ERA may be beneficial for women with a history of early pregnancy loss as the maximum is transferred at a time of optimal fertility for that woman.
• Endometriosis or Uterine Problems: But for women with conditions such as endometriosis, fibroids, or a thin uterine lining, being able to implant an embryo can be difficult and this is where the ERA test comes in handy.

ERA at Nex IVF Centre

Infertility can be complex, but at Nex IVF Centre we understand the complexities and we promise to offer our patients the most advanced and effective treatments. In addition to ERA testing, our experts perform the testing as part of a complete fertility panel. Results from the ERA test allow us to give you our personalized IVF treatment plan designed to improve your chances of success.

Enhancing IVF Success with the ERA Test at Nex IVF Centre

Today, the Embryo Transfer Receptivity Array (ERA) has changed the game in IVF with doctors now able to time embryo transfers to increase a patient’s chances of pregnancy success. If you’ve suffered infertility or unexplained IVF failures in the past, ERA could very well be your solution. Located at Nex IVF Centre, we are committed to providing you with advanced and latest fertility treatment so that you may achieve your dream of parenthood.

Want to learn more about ERA testing or find out if it is right for you? Contact us at Nex IVF Centre. We’ll be pleased to help you and answer your questions when you call our specialists. We join together to make your IVF journey smoother and more successful.