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Intrauterine Insemination (IUI) is one of the most commonly recommended fertility treatments for couples trying to conceive. It’s minimally invasive and more affordable than IVF. However, it doesn’t always guarantee success. Many couples undergo one or more IUI cycles without achieving pregnancy.
At Nex IVF Patna, we believe in providing transparent, supportive care. In this blog, we’ll explain why IUI might fail and what options you can consider next.
What Is IUI?
IUI is a fertility treatment where healthy, washed sperm are placed directly into a woman’s uterus during ovulation. This increases the chance of fertilization by bringing sperm closer to the egg. It’s often recommended for:
- Mild male factor infertility
- Unexplained infertility
- Ovulation issues
- Cervical mucus problems
Despite being a well-established method, success is not guaranteed.
Common Reasons Why IUI Might Fail
Understanding the cause of IUI failure can help improve your treatment strategy. Some of the most common reasons include:
| Reason | Details |
|---|---|
| Poor Egg Quality | Especially in women above 35, lower egg quality may reduce fertilization chances. |
| Low Sperm Quality | IUI relies on motile and healthy sperm. Low count or motility affects success. |
| Timing Issues | If insemination isn’t aligned with ovulation, fertilization may not happen. |
| Uterine or Tubal Problems | Polyps, fibroids, or blocked tubes can interfere with sperm or embryo implantation. |
| Ovulation Irregularities | No egg release or poor ovarian response reduces the chance of success. |
| Endometriosis | Can negatively impact both egg quality and uterine receptivity. |
| Unexplained Infertility | In many cases, no clear reason is found, making IUI results unpredictable. |
What to Do After a Failed IUI?
Experiencing a failed IUI cycle can be emotionally difficult, but it doesn’t mean the end of your journey.
Here’s what we recommend at Nex IVF Patna:
1. Review the Entire IUI Cycle
Your doctor will evaluate how the ovaries responded, sperm parameters, and the timing of insemination.
2. Make Lifestyle Adjustments
Quit smoking, reduce alcohol, manage stress, and focus on a healthy diet to improve fertility.
3. Consider Further Testing
Advanced diagnostics like hysteroscopy, AMH testing, or sperm DNA fragmentation can help uncover hidden causes.
4. Try Another IUI Cycle (if recommended)
Sometimes, changing medication doses or closely monitoring ovulation timing improves outcomes.
5. Move Toward IVF or ICSI
If multiple IUI cycles have failed or you have complicating factors (age, low ovarian reserve, severe male infertility), IVF or ICSI may offer a better chance.
Why Choose Nex IVF Patna?
We combine compassionate care with cutting-edge fertility solutions. When you choose Nex IVF Patna, you receive:
✔️ Personalized fertility assessments
✔️ Advanced diagnostics and lab services
✔️ Supportive counselling and care coordination
✔️ Proven success with IVF, ICSI, and IMSI treatments
Final Thoughts
IUI failure can be disappointing, but it’s not uncommon. With the right guidance and a step-by-step treatment approach, many couples go on to conceive successfully. At Nex IVF Patna, we are committed to understanding your unique needs and guiding you toward the best solution.
📞 Contact us to book a consultation and take the next step in your fertility journey.